Table 1.
Demographic and clinical characteristics of the study population.
| Body mass index (kg/m2) | P value |
||
|---|---|---|---|
| <30 (n=154) |
≥30 (n=88) |
||
| Body mass index (Kg/m2, mean and range) | 26±3 (13.8-29.9) |
36±6 (30.1-65) |
<.0001 |
| Age (years) | 53 ±17 | 51 ±15 | 0.39 |
| Men | 64% | 72% | 0.21 |
| Race | |||
| Caucasian | 63% | 64% | 0.92 |
| African American | 21% | 27% | 0.25 |
| Other | 16% | 9% | 0.12 |
| Family history of hypertrophic cardiomyopathy | 24% | 13% | 0.07 |
| Family history of sudden cardiac death | 14% | 12% | 0.72 |
| Family history of coronary artery disease | 22% | 18% | 0.53 |
| Diabetes mellitus | 8% | 15% | 0.08 |
| Dyslipidemia | 45% | 53% | 0.26 |
| Smoker | 21% | 31% | 0.17 |
| Hypertension | 37% | 55% | 0.008 |
| Systolic blood pressure at rest (mmHg) | 130 ±19 | 134 ±18 | 0.12 |
| Diastolic blood pressure at rest (mmHg) | 90 ±28 | 88 ±26 | 0.62 |
| Cardiovascular medications | |||
| Beta blockers | 67% | 68% | 0.94 |
| Calcium antagonists | 25% | 34% | 0.16 |
| Disopyramide | 3% | 3% | 0.86 |
| ACE inhibitors | 16% | 33% | 0.004 |
| Diuretics | 15% | 22% | 0.17 |
| Clinical presentation | |||
| Chest pain | 18% | 38% | 0.002 |
| Dyspnea | 42% | 57% | 0.04 |
| New York Heart Association ≥ 2 | 30% | 49% | 0.003 |
| Syncope | 11% | 13% | 0.62 |
| Paroxysmal atrial fibrillation | 10% | 8% | 0.59 |
| Persistent atrial fibrillation | 2% | 0% | 0.29 |