Table 2.
Prognostic factors for EVR: analysis of multivariate logistic regression using the Rosenbrock and quasi-Newton method
| Constant B0 | IL28B CC genotype | Age >40 years | |
|---|---|---|---|
| Regression coefficient | 0.83 | 1.63 | −1.34 |
| Standard error | 0.37 | 0.74 | 0.65 |
| t(62) | 2.23 | 2.20 | −2.06 |
| P | 0.0294 | 0.0313 | 0.0433 |
| −95 %CL | 0.09 | 0.15 | −2.65 |
| +95 %CL | 1.57 | 3.10 | −0.04 |
| Chi-square Wald | 4.97 | 4.85 | 4.25 |
| P | 0.0258 | 0.0276 | 0.0391 |
| Odds ratio for a one-unit change | 2.29 | 5.09 | 0.26 |
| −95 %CL | 1.09 | 1.16 | 0.07 |
| +95 %CL | 4.80 | 22.30 | 0.96 |
| Odds ratios range | 5.09 | 0.26 | |
| −95 %CL | 1.16 | 0.07 | |
| +95 %CL | 22.3 | 0.96 |
The parameter that were obtained indicate that the presence of the CC genotype increases the likelihood of early virological response (EVR). Age >40 reduces the likelihood of EVR
The above table contains the parameters of regression analysis. Regression coefficients are the most important parameter among the ones listed. Based on this parameter, we can determine how CC genotype and age above 40 years influence the likelihood of EVR