Figure 3.
Identification of the elements within the AR-binding region responsible for androgen responsiveness of sgk3 promoters. A–D, LNCaP cells were transfected with the luciferase reporters as indicated and then cultured in the presence or absence of 1 nM DHT. Twenty-four hours after transfection, luciferase activity of cell extracts was measured and normalized to protein concentration. Data are expressed as means ± SD from 3 independent experiments. n.s, not statistically significant; **, P < .01, by the Student t test.