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. 2014 Mar 26;306(11):F1318–F1326. doi: 10.1152/ajprenal.00036.2014

Fig. 3.

Fig. 3.

OPA1 proteolysis occurs during renal ischemia-reperfusion in mice. C57BL/6 mice were subjected to 25 min of bilateral renal ischemia followed by 48 h of reperfusion (I25R48). A: blood urea nitrogen (BUN) values for mice before (control) and I25R24 and I25R48 (n = 4). **P < 0.01. B: serum creatinine values at 48 h of reperfusion (n = 4). *P < 0.05. C: immunoblot of kidney injury molecule (Kim 1) at conditions of sham and I25R48. D: quantification of Kim 1 (n = 4). **P < 0.01. E: immunoblot of OPA1 showing OPA1 proteolysis during renal ischemia-reperfusion. F: densitometry analysis of OPA1-L2 degradation during renal ischemia-reperfusion (n = 4). **P < 0.01.