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. 2014 May 21;14:483. doi: 10.1186/1471-2458-14-483

Table 1.

Cross sectional and cohort studies on Ferritin level and of the Metabolic Syndrome

First author Year (Reference number) Country Study design Population Men (%) Age years Sample Ferritin assay Metabolic syndrome criteria Ferritin concentration (μg/l)
*Quality score
Men Women
Jehn, 2004 [11]
U.S.
Cross-sectional
NHANES III (1988–1994) U.S. Population
48
48
5,949
RIA
NCEP ATPIII
Q1:62a Q4:318a
Premenopausal: Q1:11a Q4:89a Postmenopausal: Q1:35a Q4:212a
30
Bozzini, 2005 [12]
Italy
Cross-sectional
Verona Heart Project
73
58
479
NIA
NCEP ATPII
Both genders: With MS: 124 (111–138)b Without MS: 83 (73–94)b
19
Choi, 2005 [13]
Korea
Cross-sectional
Welfare Centers of Seoul Metropolitan
0
72
959
EIA
NCEP original
 
With MS: 74 ± 2c Without MS: 59 ± 2c
28
Soto González 2006 [14]
Spain
Cross-sectional
Patients of the Endocrinoloy and Nutrition Service of Hospital
34
38
598
RIA
NCEP ATPIII
Both genders: With MS: 133.9 ± 141.1d Without MS: 66.8 ± 71.8d
31
Vari, 2007 [32]
France
Prospective cohort
DESIR cohort French people 6 years of follow up
49
47
944
NIA
NCEP ATPIII
At baseline 178 ± 90d
At baseline Premenopausal women: 56 ± 40d Postmenopausal women: 92 ± 54d
32
Shi, 2008 [15]
China
Cross-sectional
The 2002 National Nutrition and Health survey
46
40-49
2,816
RIS
NR
Q4:257 (176–500)e
Q4:170 (96–504)e
30
Sun, 2008 [16]
China
Cross-sectional
Nutrition and Health of Aging population
44
58
3,165
TIA
NCEP ATPIII
Q1:71 (68–73.2)b Q4:327 (316–340)b
Q1:52 (51–54)b Q4:231(224–239)b
30
Ryu, 2008 [17]
Korea
Cross-sectional
Korean Rural GENOMIC Cohort
38
58
1,444
N.R
NCEP ATPIII
Q1:45 ± 2f Q4:258 ± 12f
Q1:17 ± 2f Q4:131 ± 1f
32
Kim, 2011 [18]
Korea
Cross-sectional
Healthy volunteers
53
51
7,253
TIA
NCEP ATPIII
176 ± 108d
75 ± 55d
30
Park, 2012 [26]
Korea
Prospective cohort
Check-up of men in Health Promotion Center
100
44
13,084
 
International Diabetes Federation
At baseline 112 ± 64d
-------------
31
Kang, 2012 [20]
Korea
Cross-sectional
South Korean general population KNANHES IV (2007–2008)
44
48
7,346
RIA
NCEP ATPIII
Q1:46 (33, 55)g Q4:194(167, 247)g
Q1:13 [9,17]g Q4:90 (75, 114)g
27
Hämäläinen, 2012 [21]
Finland
Case–control
People invited to heath check up in 2004
45
52
766
EIA
NCEP ATPIII
With MS: 216 ± 165d Without MS: 151 ± 112d
With MS: 94 ± 75d Without MS: 61 ± 48d
28
Leiva, 2013 [19]
Chile
Cross-sectional
Research program of Risk Factors for Cardiovascular Disease of Talca
31
57
155
EIA
NCEP ATPIII
With MS: 72 (47–112)h Without MS: 55 (36–96)h
With MS: 54 (34–85)h Without MS: 27 (13–60)h
30
Chang, 2013 [22]
Taiwan
Cross-sectional
Third national nutritional and health survey in Taiwan (NAHSIT 2005-2008)
43
55
2,654
EIA
NCEP ATPIII modified
229 ± 349d
119 ± 180d
27
Li, 2013 [31] China Cross-sectional China Health and Nutrition Survey 47 51 8,441 RIA NCEP ATPIII modified Q1:52a Q4:423a Q1:12.9a Q4:142.7a 30

EIA, Electrochemiluminescence immunoassay; NIA, Nephelometric immunoassay; NR, not reported; RIA, immunoradiometric assay; TIA, immunoturbidimetric assay. *Quality score of STROBE Statement.

aMedian of quartile; bGeometric mean (95% CI); cGeometric mean ± SD; dMean ± SD; eMean of quartile (minimum-maximum); fGeometric mean ± SE; gMedian (range); hGeometric mean (range).

SD: standard deviation; SE: standard error; CI: confidence interval; MS: metabolic syndrome; Q1: quartile 1; Q4: quartile 4: T1: tertile 1; T3: tertile 3.