Table 1.
First author Year (Reference number) | Country | Study design | Population | Men (%) | Age years | Sample | Ferritin assay | Metabolic syndrome criteria |
Ferritin concentration (μg/l) |
*Quality score | |
---|---|---|---|---|---|---|---|---|---|---|---|
Men | Women | ||||||||||
Jehn, 2004 [11] |
U.S. |
Cross-sectional |
NHANES III (1988–1994) U.S. Population |
48 |
48 |
5,949 |
RIA |
NCEP ATPIII |
Q1:62a Q4:318a |
Premenopausal: Q1:11a Q4:89a Postmenopausal: Q1:35a Q4:212a |
30 |
Bozzini, 2005 [12] |
Italy |
Cross-sectional |
Verona Heart Project |
73 |
58 |
479 |
NIA |
NCEP ATPII |
Both genders: With MS: 124 (111–138)b Without MS: 83 (73–94)b |
19 |
|
Choi, 2005 [13] |
Korea |
Cross-sectional |
Welfare Centers of Seoul Metropolitan |
0 |
72 |
959 |
EIA |
NCEP original |
|
With MS: 74 ± 2c Without MS: 59 ± 2c |
28 |
Soto González 2006 [14] |
Spain |
Cross-sectional |
Patients of the Endocrinoloy and Nutrition Service of Hospital |
34 |
38 |
598 |
RIA |
NCEP ATPIII |
Both genders: With MS: 133.9 ± 141.1d Without MS: 66.8 ± 71.8d |
31 |
|
Vari, 2007 [32] |
France |
Prospective cohort |
DESIR cohort French people 6 years of follow up |
49 |
47 |
944 |
NIA |
NCEP ATPIII |
At baseline 178 ± 90d |
At baseline Premenopausal women: 56 ± 40d Postmenopausal women: 92 ± 54d |
32 |
Shi, 2008 [15] |
China |
Cross-sectional |
The 2002 National Nutrition and Health survey |
46 |
40-49 |
2,816 |
RIS |
NR |
Q4:257 (176–500)e |
Q4:170 (96–504)e |
30 |
Sun, 2008 [16] |
China |
Cross-sectional |
Nutrition and Health of Aging population |
44 |
58 |
3,165 |
TIA |
NCEP ATPIII |
Q1:71 (68–73.2)b Q4:327 (316–340)b |
Q1:52 (51–54)b Q4:231(224–239)b |
30 |
Ryu, 2008 [17] |
Korea |
Cross-sectional |
Korean Rural GENOMIC Cohort |
38 |
58 |
1,444 |
N.R |
NCEP ATPIII |
Q1:45 ± 2f Q4:258 ± 12f |
Q1:17 ± 2f Q4:131 ± 1f |
32 |
Kim, 2011 [18] |
Korea |
Cross-sectional |
Healthy volunteers |
53 |
51 |
7,253 |
TIA |
NCEP ATPIII |
176 ± 108d |
75 ± 55d |
30 |
Park, 2012 [26] |
Korea |
Prospective cohort |
Check-up of men in Health Promotion Center |
100 |
44 |
13,084 |
|
International Diabetes Federation |
At baseline 112 ± 64d |
------------- |
31 |
Kang, 2012 [20] |
Korea |
Cross-sectional |
South Korean general population KNANHES IV (2007–2008) |
44 |
48 |
7,346 |
RIA |
NCEP ATPIII |
Q1:46 (33, 55)g Q4:194(167, 247)g |
Q1:13 [9,17]g Q4:90 (75, 114)g |
27 |
Hämäläinen, 2012 [21] |
Finland |
Case–control |
People invited to heath check up in 2004 |
45 |
52 |
766 |
EIA |
NCEP ATPIII |
With MS: 216 ± 165d Without MS: 151 ± 112d |
With MS: 94 ± 75d Without MS: 61 ± 48d |
28 |
Leiva, 2013 [19] |
Chile |
Cross-sectional |
Research program of Risk Factors for Cardiovascular Disease of Talca |
31 |
57 |
155 |
EIA |
NCEP ATPIII |
With MS: 72 (47–112)h Without MS: 55 (36–96)h |
With MS: 54 (34–85)h Without MS: 27 (13–60)h |
30 |
Chang, 2013 [22] |
Taiwan |
Cross-sectional |
Third national nutritional and health survey in Taiwan (NAHSIT 2005-2008) |
43 |
55 |
2,654 |
EIA |
NCEP ATPIII modified |
229 ± 349d |
119 ± 180d |
27 |
Li, 2013 [31] | China | Cross-sectional | China Health and Nutrition Survey | 47 | 51 | 8,441 | RIA | NCEP ATPIII modified | Q1:52a Q4:423a | Q1:12.9a Q4:142.7a | 30 |
EIA, Electrochemiluminescence immunoassay; NIA, Nephelometric immunoassay; NR, not reported; RIA, immunoradiometric assay; TIA, immunoturbidimetric assay. *Quality score of STROBE Statement.
aMedian of quartile; bGeometric mean (95% CI); cGeometric mean ± SD; dMean ± SD; eMean of quartile (minimum-maximum); fGeometric mean ± SE; gMedian (range); hGeometric mean (range).
SD: standard deviation; SE: standard error; CI: confidence interval; MS: metabolic syndrome; Q1: quartile 1; Q4: quartile 4: T1: tertile 1; T3: tertile 3.