Table 2.
Subgroup | Number of studies | Odds ratio (95% CI) | I2 | P-value |
---|---|---|---|---|
Study design |
|
|
|
|
Prospective cohort |
2 |
1.59 (1.38, 1.82) |
0% |
|
Cross-sectional |
12 |
1.78 (1.51, 2.09) |
81% |
|
Case–control study |
1 |
1.65( 1.43, 1.91) |
0% |
0.551 |
Measure of association |
|
|
|
|
Odds Ratio |
13 |
1.62 (1.47, 1.79) |
47% |
|
Hazard Ratio |
2 |
1.61 (1.49, 1.75) |
37% |
0.520 |
Geographic area |
|
|
|
|
Asian |
9 |
1.67 (1.38, 2.02) |
84% |
|
Europe |
4 |
1.66 (1.50, 1.83) |
14% |
|
American |
2 |
2.41 (1.77, 3.27) |
11% |
0.239 |
Adjusted for CRP |
|
|
|
|
Yes |
9 |
1.92 (1.61, 2.30) |
78% |
|
No |
6 |
1.52 (1.36, 1.69) |
41% |
0.044 |
Quality of SCORE statement |
|
|
|
|
<30 points |
4 |
1.43 (1.27, 1.61) |
0% |
|
≥30 points |
11 |
1.87 (1.62, 2.17) |
79% |
0.038 |
Ferritin assay |
|
|
|
|
RIA |
5 |
1.93 (1.49, 2.51) |
85% |
|
TIA |
2 |
1.53 (1.08, 2.16) |
64% |
|
Others |
6 |
1.56 (1.42, 1.70) |
17% |
0.091 |
Study size, population |
|
|
|
|
<300 |
4 |
1.76 (1.512, 2.06) |
57% |
|
≥300 | 11 | 1.70 (1.46, 1.98) | 78% | 0.152 |
CRP, C-reactive protein; RIA, immunoradiometric assay; TIA, immunoturbidimetric assay.