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A: representative examples of renal SNA and ABP responses to PVN microinjection of AP5 (top) and CNQX (bottom) in euhydrated (EH) and dehydrated (DH) rats. B: summary data of peak changes of renal SNA and MAP after bilateral microinjection of AP5 or CNQX into PVN of EH (n = 7) and DH (n = 6) rats. Whereas AMPA receptor blockade had no effect in either EH or DH rats, blockade of PVN NMDA receptors significantly reduced ongoing renal SNA and MAP in DH rats only. *P < 0.05 vs. EH.
