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. Author manuscript; available in PMC: 2014 Jun 3.
Published in final edited form as: J Immunol. 2011 Nov 14;187(12):6463–6472. doi: 10.4049/jimmunol.1101171

Figure 4.

Figure 4

Substantial ex vivo IFNγ production by CD8+ cells from LCMV-infected mice. (A) B6 and Kb−/−Db−/−CIITA−/− mice were infected with 2 × 105 PFUs LCMV-Armstrong and, at days 3, 5, 8, and 12, spleens were harvested and analyzed for surface CD8〈 and intracellular IFN© by flow cytometry. (B) The percentage and total number of IFN© producing CD8α+ spleen lymphocytes was determined for B6, and Kb−/−Db−/−CIITA−/− mice at various time points post infection.