Figure 6.

Magnetic threshold was dependent on coil orientation. (A) Schematic drawing of the simulated and experimental settings showing the calculated induced electric field and two pyramidal neurons, one shifted by 1 cm in the x direction and one shifted by 1 cm in the y direction from the center of the coil. (B) Box plot of the simulated magnetic threshold ratio. The magnetic threshold (MT) was simulated once when the neuron was shifted in the x direction and once in the y direction. The ratio was obtained by dividing the MT_x by MT_y. (C) representative reconstructions of three L5 pyramidal neurons and three low threshold interneurons used in the simulations presented in (B). The apical dendrite of the pyramidal neurons was truncated to allow using the same scale for both neuronal types. (D) Box plot of the measured magnetic threshold ratio recorded from low threshold interneurons. (E) Box plot of the latency between the magnetic stimulus and the action potential recorded during the experiments in (C).