Table 2.
Biochemical results | CTRL | REPL | DEF | Effect |
---|---|---|---|---|
Plasma VitC (nmol/mL) | 51.8 ± 22.4 a | 57.3 ± 13.6 a | 4.0 ± 3.2 b | *** |
Plasma DHA% (% of total VitC) | 10.2 ± 4.9 a | 7.7 ± 2.2 a | 19.1 ± 3.8 b | *** |
Brain VitC (nmol/g tissue) | 1399 ± 143 a | 1498 ± 42 a | 495 ± 252 b | *** |
Brain DHA% (% of total VitC) | 4.5 ± 2.8 a | 3.1 ± 2.2 a | 9.5 ± 4.6 b | *** |
Brain MDA (nmol/g tissue) | 313 ± 124 a | 258 ± 58.9 a | 476 ±106 b | *** |
Brain GSH (nmol/g tissue) | 1348 ± 112 | 1407 ± 44.6 | 1341 ± 101.0 | - |
Biochemistry results of CTRL, REPL, and DEF guinea pigs from brain and plasma following a prenatal VitC deficiency and subsequent two months postnatal repletion or deficiency, compared to pre-and postnatally sufficient controls. Effect of VitC diet between three groups by one way ANOVA marked *** p < 0.0001. All values are presented as means ± SD. Values with different superscript letters are significantly different (i.e., “a” is different from “b”).