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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Neuropathol Appl Neurobiol. 2014 Apr;40(3):327–336. doi: 10.1111/nan.12093

Figure 3.

Figure 3

Histopathological characteristics of epithelioid glioblastoma (e-GB) in children. Several cytological phenotypes characterize these tumors, including epithelioid (a), rhabdoid (b), and astrocytic/gemistocytic (c). e-GBs resemble classic glioblastomas in some areas (d; all H&E, ×200). Immunoreactivity for GFAP was variable in tumor cells (e; anti-GFAP antibody, ×200). Homozygous deletion of CDKN2A was evident in two patients (f; iFISH: green and red fluorochromes targeted CDKN2A and the control locus on 9q, respectively)