Table 1.
Patient # |
Age at Diagnosis (years) |
Gender / Race | Primary Tumor Location |
Intra-Tumoral Hematoma at Diagnosis |
Metastatic Disease at Diagnosis |
Site of First Tumor Progression |
Tumor Spread Outside the CNS |
Survival (days) |
---|---|---|---|---|---|---|---|---|
1 | 10.7 | F / Caucasian | Thalamus | YES | No | Outside the CNS | YES | 144 |
2 | 11.3 | M / AA | Temporal lobe | YES | YES¶ | Leptomeningeal | YES‡ | 118 |
3§ | 10.2 | F / AA | Bi-thalamic | No | YES¶ | Outside the CNS | YES | 42 |
4 | 3.5 | M / Mixed race | Frontal Lobe | YES | YES¶ | Leptomeningeal | No | 194 |
5 | 3.5 | F / Caucasian | Hypothalamic | No | No | Leptomeningeal | No | 230 |
6§ | 5 | M / Caucasian | Thalamus | No | No | Local | No | 290 |
CSF positive for malignant cells and tumor nodule in cauda equina (patient 2), CSF positive for malignant cells only (patient 3), and multiple foci of metastatic spread in the brain (patient 4);
Tumor spread outside the CNS was documented at autopsy;
Patients 3 and 6 were only seen as consultation
Abbreviations: M, male; F, female; AA, African-American; CNS, central nervous system; CSF, cerebrospinal fluid