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. 2014 Jun 2;211(6):1063–1078. doi: 10.1084/jem.20132063

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© 2014 Liu et al.

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Figure 3. — Skin inflammation is not affected by BLT2 deficiency or aspirin treatment. (A) MPO activity in homogenates of punched skin obtained from BLT2 WT and BLT2 KO mice (n = 3 mice per group). Punch biopsies (5 mm in diameter) were obtained at 2 d after skin punching and used for the assay. (B and C) Frequency of immune cells expressing the indicated surface markers as determined by flow cytometry analysis in the punched skin of BLT2 WT and BLT2 KO mice (B, n = 3 mice per group) and WT mice with or without aspirin treatment (C, n = 3 mice per group). Aspirin treatment (0.18 mg/ml in the drinking water) was initiated at 2 d before skin punching. Punch biopsies (5 mm in diameter) were obtained at 2 and 5 d after skin punching and used for the assay. Data represent the mean ± SEM. *, P < 0.05, N.S., not significant (unpaired Student’s t test). All the results are representative of at least two independent experiments.