Table 1.
CtIP+/-53BP1−/− x CtIP+/−53BP1−/− | CtIP+/−KU80+/− x CtIP+/−Ku80+/− | |||||
Genotypes | CtIP+/+ 53BP1−/− | CtIP+/− 53BP1−/− | CtIP−/− 53BP−/− | CtIP+/+ KU80−/− | CtIP+/− KU80−/− | CtIP−/− KU80−/− |
Live-born pups | ||||||
Observed | 25 | 35 | 0 | 1 | 15 | 0 |
Expected | 15 | 30 | 15 | 8.0625 | 16.125 | 8.0625 |
Total mice screened | 60 | 129 |
CtIP+/− 53BP1−/− mice and CtIP+/−Ku80+/− were intercrossed. Genotypes and number of animals generated by the breeding are indicated.