Table 3.
CtIPT847ACtIP+/− x CtIP+/− | ||||||
Genotype | CtIP−/− | CtIP−/− | CtIP+/+ | CtIPT847A CtIP−/− | CtIPT847A CtIP+/− | CtIPT847A CtIP+/+ |
E9.5 embryos | ||||||
Observed | 0 | 2 | 1 | 0 | 14 | 6 |
Expected | 2.875 | 5.75 | 2.875 | 2.875 | 5.75 | 2.875 |
Total embryos screened | 23 |
CtIP heterozygous mice were intercrossed with one parent carrying a copy of the transgenic CtIP-T847A mutation, and embryos were genotyped at E9.5.