TABLE 1.
Day | Sample | Gram stain result | Culture result | PCR/ESI-MS result | PCR level (genome equivalents/well) | U. parvum PCR result | CRP level (mg/dl) | Antimicrobial treatment (no. of days of treatment) |
---|---|---|---|---|---|---|---|---|
−1 | Synovial fluid | No organisms seen | No growth | U. parvum | 340 | Positive | 8.27 | None |
Day of surgery | Synovial fluid | No organisms seen | No growth | U. parvum | 366 | 8.83 | Vancomycin (1) | |
Articular tissue | No organisms seen | No growth | U. parvum | 234 | Cefepime (1) | |||
PODa | ||||||||
28 | Synovial fluid | No organisms seen | No growth | U. parvum | 35 | Positive | 3.15 | Vancomycin (29), ertapenem (24) |
48b | 3.33 | Vancomycin (49), ertapenem (44) | ||||||
132 | Synovial fluid | No organisms seen | No growth | No detection | NAc | Negative | 1.97 | Doxycycline (84) |
POD, postoperative day.
On day 48, antibiotic treatment was changed to oral doxycycline based on the results of the PCR and PCR/ESI-MS testing.
NA, not available.