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. 2014 Jun;52(6):2223–2227. doi: 10.1128/JCM.00408-14

TABLE 1.

Country of origin, source of isolation, susceptibility to itraconazole with MICs, and presence or absence of TR34/L98H mutations in the cyp51A gene of A. fumigatus isolates

Serial no. Isolate no. Country of origin Source of isolation Susceptibility to ITR,d MIC (μg/ml) TR34/L98H mutation
1 E-296 Kuwait Outdoor air Susceptible, 0.5 No/no
2 E-149 Kuwait Outdoor air Susceptible, 0.38 No/no
3 E-288 Kuwait Hospital indoor air Susceptible, 0.75 No/no
4 E-298 Kuwait Hospital indoor air Susceptible, 0.38 No/no
5 E-256 Kuwait Hospital floor swab Susceptible, 0.75 No/no
6 E-262 Kuwait Hospital indoor air Susceptible, 0.38 No/no
7 E-267 Kuwait Hospital indoor air Susceptible, 0.38 No/no
8 E-142 Kuwait Hospital floor swab Susceptible, 0.38 No/no
9 Kw2287/09 Kuwait Clinical, sputum Susceptible, 0.75 No/no
10 Kw3468/10 Kuwait Clinical, sputum Susceptible, 0.047 No/no
11 Kw2893/10 Kuwait Clinical, sputum Susceptible, 0.75 No/no
12 Kw3068/10 Kuwait Clinical, sputum Susceptible, 0.75 No/no
13 Kw1830/08 Kuwait Clinical, wound swab Susceptible, 0.5 No/no
14 Kw3916/10 Kuwait Clinical, sputum Susceptible, 0.5 No/no
15 E-307 Kuwait Hospital indoor air Susceptible, 0.38 No/no
16 Kw2351/11 Kuwait Clinical, bronchoalveolar lavage specimen Susceptible, 0.38 No/no
17 Kw3328/10 Kuwait Clinical, sputum Susceptible, 0.75 No/no
18 Kw2349/11 Kuwait Clinical, bronchoalveolar lavage specimen Susceptible, 0.125 No/no
19 R-1 Kuwait Outdoor, soil sample Susceptible, 0.75 No/no
20 R-2 Kuwait Outdoor, soil sample Susceptible, 0.38 No/no
21 R-3 Kuwait Outdoor, soil sample Susceptible, 0.25 No/no
22 R-4 Kuwait Outdoor, soil sample Susceptible, 0.25 No/no
23 R-5 Kuwait Outdoor, soil sample Susceptible, 0.75 No/no
24 R-6 Kuwait Outdoor, soil sample Susceptible, 0.5 No/no
25 R-7 Kuwait Outdoor, soil sample Susceptible, 0.19 No/no
26 R-8 Kuwait Outdoor, soil sample Susceptible, 0.38 No/no
27 E-1 Kuwait Outdoor air Susceptible, 0.5 No/no
28 E-143 Kuwait Outdoor air Susceptible, 0.75 No/no
29 E-290 Kuwait Outdoor air Susceptible, 0.38 No/no
30 E-320 Kuwait Hospital indoor air Susceptible, 0.38 No/no
31 E-335 Kuwait Outdoor air Susceptible, 0.75 No/no
32 E-286 Kuwait Hospital indoor air Susceptible, 0.75 No/no
33 E-106 Kuwait Hospital indoor air Susceptible, 0.5 No/no
34 Kw1431/10 Kuwait Clinical, sputum Susceptible, 0.5 No/no
35 Kw2285/09 Kuwait Clinical, endotracheal aspirate Susceptible, 0.19 No/no
36 Kw2941/11 Kuwait Clinical, sputum Susceptible, 0.012 No/no
37 Kw3862/10 Kuwait Clinical, sputum Susceptible, 0.5 No/no
38 Kw1724/09 Kuwait Clinical, ear swab Susceptible, 0.25 No/no
39 Kw1787/10 Kuwait Clinical, skin swab Susceptible, 0.75 No/no
40 Kw2881/11 Kuwait Clinical, bronchoalveolar lavage specimen Susceptible, 0.38 No/no
41 E-76 Kuwait Hospital indoor air Resistant, >16 Yes/yes
42 E-119 Kuwait Hospital floor swab Resistant, >16 Yes/yes
43 E-218 Kuwait Outdoor air Resistant, >16 Yes/yes
44 E-454 Kuwait Hospital floor swab Resistant, >16 Yes/yes
45 R-15 Kuwait Soil sample Resistant, >16 Yes/yes
46 R-18 Kuwait Soil sample Resistant, >16 Yes/yes
47 R-44 Kuwait Soil sample Resistant, >16 Yes/yes
48 10-03-18-79 India Soil sample Resistant, >16 Yes/yes
49 10-03-18-83 India Soil sample Resistant, >16 Yes/yes
50 10-03-19-75 India Soil sample Resistant, >16 Yes/yes
51 10-03-19-73 India Soil sample Resistant, >16 Yes/yes
52 10-03-18-81 India Soil sample Resistant, >16 Yes/yes
53 10-03-15-27 France Clinical, sputum Resistant, >16 No/noa
54 10-03-18-82 India Soil sample Resistant, >16 Yes/yes
55 10-03-15-38 India Clinical, sputum Resistant, >16 Yes/yes
56 10-03-19-72 India Soil sample Resistant, >16 Yes/yes
57 10-03-18-80 India Soil sample Resistant, >16 Yes/yes
58 10-03-19-74 India Soil sample Resistant, >16 Yes/yes
59 10-03-15-19 France Clinical, sputum Resistant, >16 No/nob
60 10-03-19-70 India Soil sample Resistant, >16 Yes/yes
61 10-03-19-71 India Soil sample Resistant, >16 Yes/yes
62 10-04-15-05 The Netherlands Clinical, sputum Resistant, >16 Yes/yes
63 10-01-02-62 The Netherlands Clinical, sputum Resistant, >16 Yes/yes
64 10-01-02-27 The Netherlands Clinical, sputum Resistant, >16 Yes/yes
65 10-04-15-16 The Netherlands Clinical, sputum Resistant, >16 Yes/yes
66 10-01-13-76 The Netherlands Clinical, sputum Resistant, >16 No/noc
67 10-01-12-86 The Netherlands Clinical, sputum Resistant, >16 Yes/yes
68 10-01-13-15 The Netherlands Clinical, sputum Resistant, >16 Yes/yes
69 10-04-15-12 The Netherlands Clinical, sputum Resistant, >16 Yes/yes
70 10-04-15-03 The Netherlands Clinical, sputum Resistant, >16 Yes/yes
71 10-01-04-26 The Netherlands Clinical, sputum Resistant, >16 Yes/yes
72 10-01-04-22 The Netherlands Clinical, sputum Resistant, >16 Yes/yes
73 10-03-16-61 India Soil sample Resistant, >16 Yes/yes
74 10-01-13-23 The Netherlands Clinical, sputum Resistant, >16 Yes/yes
75 10-03-16-63 India Clinical, sputum Resistant, >16 Yes/yes
a

This isolate contained an M220R mutation in cyp51A.

b

This isolate contained a G54E mutation in cyp51A.

c

This isolate contained a G54W mutation in cyp51A.

d

ITR, itraconazole.