TABLE 1.
Characteristics of all adult patients with a hematologic malignancy (HM) and a culture yielding Candida kefyr between 2004 and 2010 (n = 83)
| Characteristicd | n (%) (except for age) |
|---|---|
| Demographic data | |
| Age in yr, mean (range) | 48.7 (18–73) |
| Gender, male | 44 (53.0) |
| Ethnicity | |
| White | 52 (62.7) |
| Black | 16 (19.3) |
| Hispanic | 5 (6.0) |
| Asian | 2 (2.4) |
| Other | 8 (9.0) |
| Underlying disease | |
| Hematologic malignancya | |
| AML | 57 (68.7) |
| ALL | 8 (9.6) |
| Other AL | 6 (7.2) |
| MDS | 1 (1.2) |
| CML | 3 (3.6) |
| MM | 2 (2.4) |
| Lymphoma | 6 (7.2) |
| SCTa | |
| Autologous | 1 (1.2) |
| Allogeneic | 3 (3.6) |
| Chemotherapy type (AML only; n = 57) | |
| Induction | 35 (61.4) |
| Reinduction | 15 (26.3) |
| Consolidation | 5 (8.8) |
| None | 2 (3.5) |
| Clinical manifestation | |
| Colonization | 69 (83.1) |
| Invasive candidiasis | 8 (9.6) |
| Otherb | 6 (7.2) |
| Timingc | |
| <2 wk | 17 (20.5) |
| >2 wk | 66 (79.5) |
a
Excluding patients with relapsing hematologic malignancy after SCT, undergoing salvage chemotherapy at the time of C. kefyr colonization.
b
Other included the following 6 cases: 5 patients with asymptomatic candiduria and 1 patient with a polymicrobial perirectal abscess.
c
Time between admission to hospital and first culture yielding C. kefyr.
d
Abbreviations: AML, acute myelogenous leukemia; ALL, acute lymphoblastic leukemia; AL, acute leukemia; MDS, myelodysplastic syndrome; CML, chronic myeloid leukemia; MM, multiple myeloma; SCT, stem cell transplant.