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. 2012 Sep 17;30(6):1287–1293. doi: 10.3892/ijmm.2012.1126

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Copyright © 2012, Spandidos Publications

This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.

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KRAP expression in the mucous cells and the chief cells of the mouse stomach. (A–D) Fluorescent confocal images of stomach sections for KRAP (red), filamentous actin (F-actin) with phalloidin (green), and the merged photo. Low magnification images from the pit region to the base region of gastric glands from wild-type (A) or KRAP-deficient (B) mice. Asterisk and arrows indicate gastric lumen and muscularis mucosae beneath the base region, respectively. (C) High magnification images of the pit region of gastric glands. Asterisk indicates gastric lumen. (D) High magnification images of the base regions of gastric glands. Asterisks and arrowheads indicate the parietal cells and the apical membranes of the chief cells, respectively. (E) Fluorescent confocal images of the base regions of gastric glands for KRAP (red), ZO-1 (green), and the merged photo. Blue, 4′,6-diamidino-2-phenylindole (DAPI) staining; scale bar, 50 μm.