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. 2014 Apr 30;4(4):140043. doi: 10.1098/rsob.140043

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© 2014 The Authors. Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/3.0/, which permits unrestricted use, provided the original author and source are credited.

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Figure 5. — Analysis of genetic interactions between eic1 or eic2 mutants and mutations in Cnp1^CENP-A or Cnp1^CENP-A assembly factors. (a) eic1⁺:hyg^R and eic1-1 cells display reduced growth when combined with mutations in mis18, scm3, cnp1 or mis6. (b) eic2Δ cells display genetic interactions when combined with mis18-262 and scm3-139, but not eic1-1. Five-fold serial dilutions of cells spotted on YES + Phloxine B media and incubated at the indicated temperatures; dead cells stain dark pink. (c) A tabular summary of genetic interactions analysed in this study. s.s, synthetic sick/reduced growth; s.l, synthetic lethal; n.d., not determined; —, no interaction detected.