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The eukaryotic translation as an RFM model with feedback. (a) Illustration of the cap-dependent eukaryotic translation mechanism (explanation in the main text); for simplicity, other proteins, as well as a second eIF4A molecule known to interact with eIF4G, have been omitted. (b) The modelling of the cap-dependent eukaryotic translation mechanism by the RFMIO with feedback. (Online version in colour.)
