Table III.

Prediction results of 20-gene rEASP signature on three test sets

	RSFa	Cox modelb	HR	Log rank testc	P
	Test error rate	P		95% Confidence interval
Okayama test set (n = 226)
	29.9%	0.0004
Low risk			1		0.002
Medium risk			2.37	1.03–5.46
High risk			3.75	1.70–8.28
Raponi test set (n = 129)
	36.4%	0.007
Low risk			1		0.02
Medium risk			2.38	1.12–5.10
High risk			2.79	1.32–5.90
Bild test set (n = 111)
	35.6%	0.002
Low risk			1		0.03
Medium risk			1.54	0.78–3.02
High risk			2.34	1.24–4.42

^aRSF prediction model built from the 442 training set including 20 genes, age, gender and stage.

^bMortality risk index (MRI) as continuous value, LRT was used in univariate Cox model.

^cMRI separated test patients to three risk groups (low, medium and high-risk, one-third in each group).