Figure 8.

The absence of methylated H3-K4 is correlated to a defect in the induction of middle meiotic genes (SK1 background). The graph presents the expression level of the meiotic genes belonging to the different classes previously defined (Chu et al, 1998), 2 and 4 h after induction of sporulation of WT, swd3Δ, and set1Δ strains. Within each class and for each time point, the genes were ordered, from left to right, according to their expression level in the wild type. Log-expression levels of sporulation genes in the wild type, set1Δ, and swd3Δ are plotted as black circles, red triangles, and blue squares, respectively. Me: metabolic, E I: early I, E II: early II, E-M: early-mid, Mi: middle, M-L: mid-late, L: late (according to Chu et al, 1998).