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. 2014 Feb 7;35(6):1341–1351. doi: 10.1093/carcin/bgu042

Fig. 5.

Fig. 5.

Cancer cell-associated FASN regulates functional properties of ECs. (A and B) The effect of FASN expression in CRC cells on proliferation of HMVEC-L measured by MTS assay. ECs were cultured on control or conditioned medium for 48h. (C) The effect of VEGF189 knockdown in CRC cells on proliferation of HMVEC-L. (D) Migration of HMVEC-L cells toward CRC cells with altered expression of FASN for 20h. (E) The effect of FASN expression in CRC cells on HMVEC-L tubulogenesis. The length of tubules was quantified after 8h of exposure to conditioned medium (Nikon software). *P < 0.05 versus control.