FIG. 1.
T2 MRI. (A) Representative T2 maps are shown for vehicle- and methylene blue (MB)-treated animals at 3 h, and 1, 2, 7, and 14 days post-traumatic brain injury (TBI). The arrows indicate hyperintense lesions in the ipsilesional cortex. The white boxes in the second panel indicate the enlarged image of the lesion area demonstrated to the right of each panel to further demonstrate the evolution of the lesion with time. (B) Bar graph shows the progression of lesion volumes in MB-treated animals compared with vehicle-treated animals (mean±SEM, n=6 per group,*p<0.05).