Fig. 3.

Inflammatory cell accumulation during compensatory hypertrophy. Macrophages (A) and neutrophils (B) were quantified as number of cells stained positively for F4/80 or Ly6G antigen, respectively. Peak macrophage accumulation was markedly reduced by NS-398 treatment. NS-398 treatment did not affect peak neutrophil accumulation and only reduced neutrophil number at day 5, when neutrophil content had already declined to near control values. Data are presented as means ± SD; n = 4–8 muscles/group. ‡Significantly different from vehicle at same time point (P ≤ 0.05).