Table 1.

Biometric Data

		Weight (g)	LV/BW	RV/BW	Lung/BW
WKY	8 weeks	190±10	2.24±0.19	0.7±0.16	4.38±0.47
	12 weeks	300±11	2.18±0.10	0.58±0.07	3.47±0.22
	16 weeks	309±11	2.17±0.08	0.58±0.05	3.43±0.17
	20 weeks	325±16	2.13±0.08	0.56±0.11	3.29±0.24
	24 weeks	399±31	2.13±0.06	0.55±0.04	3.30±0.20
SHR	8 weeks	213±5	2.44±0.08	0.56±0.03	4.39±0.19
	12 weeks	278±12	2.59±0.10*	0.56±0.06	3.75±0.21
	16 weeks	323±5	2.54±0.15*	0.47±0.06	3.52±0.21
	20 weeks	365±12	2.63±0.07*	0.43±0.06	3.4±0.24
	24 weeks	369±29	2.81±0.31*	0.64±0.14	3.8±0.30
SHR + L732138	24 weeks	356±36	2.6±0.20*	0.54±0.06	3.88±0.25

Data is reported as mean values ± standard deviation. A 2-way ANOVA with a Bonferonni post-test was used to compare age-matched strains from 8 to 24 weeks of age.

^*p < 0.05.