Table 1. Isolated germ-line VH genes after the third round of TAPE.
V gene name | % of VH after TAPEa | % of VH before TAPEb | Foldincreasec |
VH3-7 | 6.5 | 4.3 | 1.5 |
VH3-9 | 0.6 | 2.1 | 0.3 |
VH3-15 | 7.1 | 3.9 | 1.8 |
VH3-21 | 1.3 | 6.1 | 0.2 |
VH3-23 | 14.3 | 16.0 | 0.9 |
VH3-30 | 46.8 | 11.4 | 4.1 |
VH3-33 | 1.3 | 2.9 | 0.4 |
VH3-43 | 0.6 | 0.4 | 1.5 |
VH3-48 | 7.1 | 3.9 | 1.8 |
VH3-49 | 0.6 | 0.4 | 1.5 |
VH3-53 | 0.6 | 1.0 | 0.6 |
VH3-72 | 0.6 | 1.0 | 0.6 |
VH3-74 | 7.1 | 2.5 | 2.8 |
others | 0 | 13.7 | - |
VH3 family | 94.8 | 70.1 | 1.4 |
VH1-2 | 0.6 | 1.4 | 0.4 |
VH1-8 | 0.6 | 0.0 | - |
VH1-46 | 0.6 | 3.5 | 0.2 |
VH1-69 | 0.6 | 4.7 | 0.1 |
others | 0 | 9.7 | - |
VH1 family | 2.6 | 19.4 | 0.1 |
VH5-51 | 1.3 | 4.3 | 0.3 |
VH5-a | 1.3 | 5.7 | 0.2 |
others | 0 | 0.7 | - |
VH5 family | 2.6 | 10.5 | 0.2 |
Proportion of each identified VH gene among the 154 sequences selected after TAPE.
Proportion of each identified VH gene among 144 sequences randomly selected from the library.
Ratio of ‘% of VH gene after TAPE’ to ‘% of VH gene before TAPE’.