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. 2014 Jun 3;9(6):e98210. doi: 10.1371/journal.pone.0098210

Table 3. Correlation between diffusion tensor imaging (DTI) abnormalities and cognitive function after adjustments for age, sex, and education in HIV-negative chronic meningitis.

NP Test DTI Metrics Anatomical Lobe Brodmann Area White Matter Tract Correlation (r) p value
Attention Function
Digit Span MD Cingulate Gyrus 32 R Superior Corona Radiata −0.266 0.044
Orientation FA Para-hippocampal Gyrus 19 R Inferior Longitudinal Fasciculus 0.365 0.004
AD Para-hippocampal Gyrus 19 L Inferior Longitudinal Fasciculus −0.450 <0.001
AD Cingulate Gyrus 32 R Superior Corona Radiata −0.428 0.001
RD Para-hippocampal Gyrus 19 L Inferior Longitudinal Fasciculus −0.529 <0.001
RD Cingulate Gyrus 32 R Superior Corona Radiata −0.331 0.010
RD Para-hippocampal Gyrus 19 R Inferior Longitudinal Fasciculus −0.454 <0.001
MD Para-hippocampal Gyrus 19 L Inferior Longitudinal Fasciculus −0.543 0.000
MD Cingulate Gyrus 32 R Superior Corona Radiata −0.380 0.003
MD Para-hippocampal Gyrus 19 R Inferior Longitudinal Fasciculus −0.434 0.001
Executive Function
Digit Symbol Coding FA Para-hippocampal Gyrus 19 L Inferior Longitudinal Fasciculus 0.275 0.040
RD Lentiform Nucleus L WM close to Globus Pallidus −0.413 0.002
MD Lentiform Nucleus L WM close to Globus Pallidus −0.370 0.005
Similarity FA Para-hippocampal Gyrus 19 L Inferior Longitudinal Fasciculus 0.343 0.009
AD Cingulate Gyrus 24 R Cingulum −0.362 0.006
AD Cingulate Gyrus 32 R Superior Corona Radiata −0.416 0.001
AD Precentral Gyrus 6 L Superior Longitudinal Fasciculus −0.268 0.044
AD Cingulate Gyrus 24 L Superior Corona Radiata −0.337 0.010
RD Cingulate Gyrus 24 R Cingulum −0.361 0.006
RD Cingulate Gyrus 32 R Superior Corona Radiata −0.418 0.001
RD Cingulate Gyrus 24 L Superior Corona Radiata −0.364 0.005
MD Cingulate Gyrus 24 R Cingulum −0.375 0.004
MD Cingulate Gyrus 32 R Superior Corona Radiata −0.432 0.001
MD Cingulate Gyrus 24 L Superior Corona Radiata −0.356 0.006
Picture Arrangement FA Para-hippocampal Gyrus 19 R Inferior Longitudinal Fasciculus 0.290 0.030
FA Lentiform Nucleus L WM close to Globus Pallidus 0.298 0.026
Information FA Para-hippocampal Gyrus 19 L Inferior Longitudinal Fasciculus 0.287 0.028
FA Cingulate Gyrus 24 R Cingulum 0.260 0.047
FA Cingulate Gyrus 32 R Superior Corona Radiata 0.282 0.031
FA Lentiform Nucleus L WM close to Globus Pallidus 0.319 0.014
RD Cingulate Gyrus 32 R Superior Corona Radiata −0.332 0.010
RD Cingulate Gyrus 24 L Superior Corona Radiata −0.268 0.040
MD Cingulate Gyrus 32 R Superior Corona Radiata −0.313 0.016
Comprehension FA Cingulate Gyrus 24 R Cingulum 0.279 0.033
AD Cingulate Gyrus 32 R Superior Corona Radiata −0.429 0.001
AD Cingulate Gyrus 24 L Superior Corona Radiata −0.322 0.013
RD Cingulate Gyrus 24 R Cingulum −0.285 0.029
RD Cingulate Gyrus 32 R Superior Corona Radiata −0.393 0.002
RD Cingulate Gyrus 24 L Superior Corona Radiata −0.328 0.011
MD Cingulate Gyrus 32 R Superior Corona Radiata −0.421 0.001
MD Cingulate Gyrus 24 L Superior Corona Radiata −0.329 0.011
Visuo-Construction Function
Picture Complete FA Para-hippocampal Gyrus 19 R Inferior Longitudinal Fasciculus 0.295 0.026
Block Design FA Para-hippocampal Gyrus 19 L Inferior Longitudinal Fasciculus 0.311 0.019
FA Para-hippocampal Gyrus 19 R Inferior Longitudinal Fasciculus 0.302 0.023
RD Para-hippocampal Gyrus 19 R Inferior Longitudinal Fasciculus −0.285 0.032
RD Lentiform Nucleus L WM close to Globus Pallidus −0.309 0.019