Table II.
Association between potential risk factors with the severity of cerebral artery stenosis.
| Cerebral artery stenosis | |||||
|---|---|---|---|---|---|
|
|
|||||
| Risk factor | Narrowing ≤50% | Narrowing >50% | Total | Test statistic | P-value |
| Gender, n (%) | |||||
| Male | 185 (68.0) | 234 (69.6) | 419 (68.9) | 0.186 | 0.666 |
| Female | 87 (32.0) | 102 (30.4) | 189 (31.1) | ||
| Diabetes, n (%) | |||||
| No | 221 (81.3) | 209 (62.2) | 430 (70.7) | 26.339 | <0.001 |
| Yes | 51 (18.8) | 127 (37.8) | 178 (29.3) | ||
| Hypertension, n (%) | |||||
| No | 79 (29.0) | 50 (14.9) | 129 (21.2) | 18.039 | <0.001 |
| Yes | 193 (71.0) | 286 (85.1) | 479 (78.8) | ||
| Hyperlipidemia, n (%) | |||||
| No | 154 (56.6) | 149 (44.5) | 303 (49.9) | 8.850 | 0.003 |
| Yes | 118 (43.4) | 186 (55.5) | 304 (50.1) | ||
| Smoking, n (%) | |||||
| No | 185 (68.0) | 195 (58.0) | 380 (62.5) | 6.387 | 0.011 |
| Yes | 87 (32.0) | 141 (42.0) | 228 (37.5) | ||
| Wine consumption, n (%) | |||||
| No | 246 (90.4) | 281 (83.6) | 527 (86.7) | 6.037 | 0.014 |
| Yes | 26 (9.6) | 55 (16.4) | 81 (13.3) | ||
| Age, yearsa | 60.7±12.1 | 65.8±10.4 | −5.6 | <0.01 | |
| Systolic blood pressure, mmHga | 147.9±24.9 | 151.4±22.7 | −1.8 | 0.065 | |
| Diastolic blood pressure, mmHga | 84.0±12.7 | 84.0±12.0 | 0.026 | 0.979 | |
| Platelet count (109/l)a | 237.345±78.032 | 245.263±78.838 | −1.229 | 0.220 | |
| International normalized ratioa | 1.029±0.101 | 1.020±0.118 | 0.884 | 0.377 | |
| Plasma fibrinogen (g/l)a | 3.460±0.859 | 3.871±1.045 | −5.124 | <0.001 | |
| Total cholesterol (mmol/l)a | 4.862±1.199 | 5.023±1.206 | −1.632 | 0.103 | |
| Triglyceride (mmol/l)a | 1.642±0.996 | 1.753±1.140 | −1.27 | 0.204 | |
| HDL (mmol/l)a | 1.191±0.447 | 1.116±0.491 | 1.942 | 0.053 | |
| LDL (mmol/l)a | 2.715±1.011 | 2.846±0.990 | −1.598 | 0.111 | |
| HLRa | 0.520±0.408 | 0.444±0.252 | 2.686 | 0.008 | |
| Fasting blood glucose (mmol/l)a | 6.000±2.149 | 6.846±3.188 | −3.874 | <0.001 | |
| Glycated hemoglobin (%)a | 6.415±1.837 | 7.009±1.985 | −3.115 | 0.002 | |
| Homocysteine (μmol/l)a | 14.084±4.669 | 14.992±6.561 | −1.615 | 0.107 | |
a
Mean ± SD.
HDL, high-density lipoprotein; LDL, low-density lipoprotein; HLR, HDL/LDL ratio.