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. 2014 Apr 3;7(6):1611–1616. doi: 10.3892/etm.2014.1662

Figure 3.

Figure 3

Synergistic effect of RES and DOX on DOX cellular accumulation in MCF-7 and MCF-7/DOX (DOX-resistant MCF-7 cells) cells. (A) MCF-7 cells or (B) MCF-7/DOX cells were exposed to serial dilutions of RES in combination with 4 μM DOX (triangle), 16 μM DOX (diamond) or 64 μM DOX (circle) for 3 h. The cellular DOX concentration was determined by fluorescence spectroscopy. P<0.01, compared with the MCF-7 cells. DOX, doxorubicin; RES, resveratrol.