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. 2014 May 23;9:2439–2458. doi: 10.2147/IJN.S58487

Figure 3.

Figure 3

Efficacy of drug-loaded gelatin fiber mats against yeast strains. The antifungal activity against Candida albicans strains is expressed as the zone of inhibition measured by radial diffusion assay. Fiber mats loaded with (A) amphotericin B (*P<0.05 compared to C. albicans ATCC 10231 strains; **P<0.01 compared to C. albicans ATCC 10231 strains; @@P<0.01 compared to C. albicans ATCC 2091 strains; @@@P<0.001 compared to C. albicans ATCC 2091 strains; #P<0.05 compared to C. albicans ATCC 24433); (B) natamycin (*P<0.05 compared to C. albicans ATCC 10231 strains); (C) terbinafine (***P<0.001 compared to all the groups); (D) itraconazole (***P<0.01 compared to all the groups except C. albicans ATCC 24433 strains; @@@P<0.001 compared to all the groups except C. albicans ATCC 2091 strains); and (E) fluconazole. ***P<0.001 compared to all the groups. (F) Representative photographs showing the zone of inhibition of gelatin (upper panel) and amphotericin B-loaded gelatin (lower panels) fiber mats.

Note: The absence of bars in the graph indicates no inhibition against the particular strain.

Abbreviation: ATCC, American Tissue Culture Collection.