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. 2014 May 23;9:2581–2595. doi: 10.2147/IJN.S63472

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© 2014 Dumont et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Size and stability of biofunctionalized MnPB nanoparticles.

Notes: (A) Size distribution of MnPB-A488-ANG2 after each functionalization step. Hydrodynamic size distributions of the MnPB nanoparticles, MnPB nanoparticles coated with avidin-Alexa Fluor 488 (MnPB-A488), and MnPB-A488 modified with biotinylated anti-neuron-glial antigen 2 (MnPB-A488-ANG2), respectively. (B) Temporal stability of MnPB nanoparticles and MnPB-A488-ANG2 in Milli-Q water and Dulbecco’s Modified Eagle’s Medium for up to 4 days post synthesis.

Abbreviations: MnPB, manganese-containing Prussian blue; A488, avidin-Alexa Fluor 488; ANG2, anti-neuron-glial antigen 2 antibody; DMEM, Dulbecco’s Modified Eagle’s Medium.