Table 1.
Demographic and clinical characteristics of lung cancer patients
| Characteristics, n (%)/mean ± SD | All (n=104) |
Current MDD (n=15) |
Non-MDD (n=89) |
P-value |
|---|---|---|---|---|
| Age, years | 61.5±9.4 | 57.8±10.6 | 62.1±9.1 | 0.104 |
| Male | 54 (51.9%) | 8 (53.3%) | 46 (51.7%) | 0.906 |
| Education, years | 0.969 | |||
| None | 7 (6.7%) | 1 (6.7%) | 6 (6.7%) | |
| 1–6 | 70 (67.3%) | 10 (66.7%) | 60 (67.4%) | |
| 7–9 | 3 (2.9%) | 0 | 3 (3.4%) | |
| 10–12 | 5 (4.8%) | 1 (6.7%) | 4 (4.5%) | |
| ≥13 | 19 (18.3%) | 3 (20.0%) | 16 (18.0%) | |
| Marital status | 1.000 | |||
| Single | 4 (3.8%) | 0 | 4 (4.5%) | |
| Married | 81 (77.9%) | 13 (86.7%) | 68 (76.4%) | |
| Separated | 2 (1.9%) | 0 | 2 (2.2%) | |
| Widowed | 17 (16.3%) | 2 (13.3%) | 15 (16.9%) | |
| Support | 1.000 | |||
| No | 1 (1.0%) | 0 | 1 (1.1%) | |
| Yes | 103 (99.0%) | 15 (100%) | 88 (98.9%) | |
| Occupation | 0.139 | |||
| Unemployed | 60 (57.7%) | 10 (66.7%) | 50 (56.2%) | |
| Employee | 13 (12.5%) | 4 (26.7%) | 9 (10.1%) | |
| Owner | 6 (5.8%) | 0 | 6 (6.7%) | |
| Government service | 5 (4.8%) | 1 (6.7%) | 4 (4.5%) | |
| State enterprise or private | 2 (1.9%) | 0 | 2 (22.2%) | |
| Others | 18 (17.3%) | 0 | 18 (20.2%) | |
| Annual income (US$)($1 = ฿30) | 0.955 | |||
| ≤2,000 | 73 (70.2%) | 12 (80.0%) | 61 (68.5%) | |
| 2,001–4,000 | 12 (11.5%) | 1 (67.0%) | 11 (12.4%) | |
| 4,001–6,000 | 5 (4.8%) | 0 | 5 (5.6%) | |
| ≥6,000 | 14 (13.5%) | 2 (13.3%) | 12 (13.5%) | |
| Debt | 0.318 | |||
| Yes | 47 (45.2%) | 5 (33.3%) | 42 (47.2%) | |
| No | 57 (54.8%) | 10 (66.7%) | 47 (52.8%) | |
| Duration of disease, months | 16.4±18.7 | 19.5±22.1 | 15.8±18.1 | 0.450 |
| Stage of cancer | 1.000 | |||
| I | 5 (4.8%) | 0 | 5 (5.6%) | |
| II | 6 (5.8%) | 1 (6.7%) | 5 (5.6%) | |
| III | 21 (20.2%) | 3 (20.0%) | 18 (20.2%) | |
| IV | 72 (69.2%) | 11 (73.3%) | 61 (68.5%) | |
| Number of treatment method(s) | 0.412 | |||
| One | 50 (48.1%) | 7 (46.7%) | 43 (48.3%) | |
| Two | 43 (41.3%) | 5 (33.3%) | 38 (42.7%) | |
| Three | 11 (10.6%) | 3 (20.0%) | 8 (9.0%) | |
| Current line of chemotherapy | 0.107 | |||
| First-line | 34 (32.7%) | 2 (13.3%) | 32 (36.0%) | |
| Before second-line | 27 (26.0%) | 4 (26.7%) | 23 (25.8%) | |
| Second-line | 19 (18.3%) | 5 (33.3%) | 14 (15.7%) | |
| Before third-line | 15 (14.4%) | 2 (13.3%) | 13 (14.6%) | |
| Third-line | 5 (4.8%) | 0 | 5 (5.6%) | |
| Completed | 4 (3.8%) | 2 (13.3%) | 2 (2.2%) | |
| Charlson Comorbidity Index scores | 7.0±2.4 | 7.7±2.7 | 6.9±2.3 | 0.191 |
| Chalder Fatigue Scale scores | 18.4±5.9 | 25.3±4.5 | 17.2±5.3 | <0.001 |
| FACT-L scores | ||||
| Physical well-being | 19.9±6.2 | 12.3±5.3 | 21.1±5.4 | <0.001 |
| Social/family well-being | 21.1±4.3 | 19.2±4.5 | 21.4±4.2 | 0.112 |
| Emotional well-being | 19.9±3.8 | 15.9±4.3 | 20.6±3.3 | <0.001 |
| Functional well-being | 17.6±6.0 | 11.4±4.7 | 18.6±5.6 | <0.001 |
| Additional concerns | 20.1±5.3 | 13.8±4.4 | 21.2±4.7 | <0.001 |
| Sum of FACT-L scores | 98.6±19.2 | 72.7±15.4 | 102.9±16.1 | <0.001 |
| VAS for pain scores | 2.9±2.8 | 4.7±2.7 | 2.6±2.7 | 0.008 |
| PSQI scores | 6.3±4.4 | 11.5±4.5 | 5.4±3.8 | <0.001 |
| PHQ-9 scores | 6.3±6.6 | 18.6±4.9 | 4.2±4.0 | <0.001 |
Abbreviations: SD, standard deviation; MDD, major depressive disorder; FACT-L, Functional Assessment of Cancer Therapy – Lung; VAS, visual analog scale; PSQI, Pittsburgh Sleep Quality Index; PHQ, Patient Health Questionnaire.