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. 2014 May 24;7:807–813. doi: 10.2147/OTT.S62707

Table 4.

Lung dosimetric parameters to predict radiation peneumonitis with an ROC curve

AUC 95% CI Z-statistic P-value (area =0.5) Youden index J Associated criterion Sensitivity Specificity
MLD (cGy) 0.878±0.0829 0.680–0.975 4.559 <0.0001 0.6889 >1,027 88.9 80.0
V5 (%) 0.815±0.113 0.605–0.942 2.782 0.0054 0.7111 >44 77.8 93.3
V10 (%) 0.819±0.104 0.609–0.944 3.055 0.0022 0.6222 >29 88.9 73.3
V15 (%) 0.822±0.0985 0.613–0.947 3.270 0.0011 0.6000 >27 66.7 93.3
V20 (%) 0.889±0.0771 0.694–0.979 5.044 <0.0001 0.7111 >22 77.8 93.3
V30 (%) 0.881±0.0692 0.684–0.976 5.514 <0.0001 0.6000 >17 66.7 93.3

Abbreviations: ROC, receiver operating characteristic; AUC, area under the curve; CI, confidence interval; MLD, mean lung dose.