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. Author manuscript; available in PMC: 2014 Jun 3.
Published in final edited form as: Genet Med. 2011 Jun;13(6):528–538. doi: 10.1097/GIM.0b013e31820a780f

Table 2.

Concordance of mPCR-CE and SB Analysis in Methylation Assessments of Clinical Samples with ≥55 CGG Repeats. Samples were selected from PCR sizing results and compared with SB analysis within genotype and methylation categories based on the longest allele within the sample. Methylation status was compared according to the resolution limits of SB analysis. mPCR-CE, FMR1 methylation PCR-Capillary Electrophoresis; SB, Southern blot.

Genotype and Methylation Status Southern Blot mPCR-CE
Full Mutation Samples (>200 CGG)
  Fully methylated 24 24
  Partially methylated 8 8
  Unmethylated 1 1
Premutation Samples (55-200 CGG)
  Fully methylated 2 2
  Partially methylated 17 17
  Unmethylated 11 11