Figure 2. Clotrimazole inhibits colony formation of OSCC cells.

OSCC cells (CAL27, SCC25, and UM1) grown in 6-well plates (1000 cells/well) were incubated with various concentrations of clotrimazole (0, 10, 20 and 30 µM) for two weeks. Cell colonies were stained and counted as described in the Methods section. The results presented as mean ± standard deviation values for three independent experiments. *P<0.05; **P<0.01 compared with solvent control.