FIGURE 1.
The location of the D166V mutation in myosin RLC pictured in the regulatory domain of scallop myosin (1WDC) [49]: The MHC is labeled in dark blue and the RLC in red, the D166V mutation (in yellow) and the Ca2+-Mg2+ binding site (in white). The hypothetical serine phosphorylation site has been indicated (dashed green line) since the region of the RLC containing the Serine 15 site has not been resolved in any of the available myosin crystal structures.