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. Author manuscript; available in PMC: 2015 Jun 15.
Published in final edited form as: Arch Biochem Biophys. 2014 Jan 31;0:117–127. doi: 10.1016/j.abb.2014.01.015

Figure 7. Force distribution throughout the half-sarcomere at 70% myosin content.

Figure 7

Average force borne by A–B) thick-filaments, C–D) cross-bridges, and E–F) thin-filaments is shown for simulations with kxb values of 3 pN nm−1when myosin content decreased randomly (panels A, C, E) and uniformly (panels B, D, F) along thick-filaments (pCa=4.0 and SL=2.3 µm). Note that thick- and thin-filament color bars ranges 0–250 pN (as in Fig. 6), while cross-bridge color bar range was reduced to −1.5–4.5 pN.