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. Author manuscript; available in PMC: 2015 Jun 15.
Published in final edited form as: Arch Biochem Biophys. 2014 Jan 27;0:50–59. doi: 10.1016/j.abb.2014.01.019

Fig. 1. Superimposed Ca2+ transients and shortening traces obtained in TG-ssTnI and NTG young and older adult myocytes.

Fig. 1

Fluorescence signals (expressed as F/F0) from Ca2+ transients of young myocytes recorded during a twitch (A), caffeine application in NT solution (B) and caffeine in Na- and Ca-free solution (C). Re-lengthening and shortening (expressed as a percentage of the total cell length) are depicted in the lower panel for twitch (D), contracture under caffeine in NT (E) and contracture under caffeine in Na- and Ca-free solution (F). Fluorescence signals (expressed as F/Fo) for older adult myocytes during a twitch (G), contractures induced by caffeine application in NT solution (H) and in Na- and Ca-free solution (I). Shortening traces (expressed as percentage of total cell length) for a twitch (J), CaffNT (K) and Caff00 (L). Note the larger amplitudes and longer duration in older TG-ssTnI myocytes twitch and contractures compare to older NTG, which are opposite the results obtained from the young group of myocytes.