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. Author manuscript; available in PMC: 2015 Jun 15.
Published in final edited form as: Arch Biochem Biophys. 2014 Jan 27;0:50–59. doi: 10.1016/j.abb.2014.01.019

Fig. 5. Comparison of the effects of caffeine on Ca2+-sensitivity of force development in myofilaments of TG-ssTnI and NTG hearts.

Fig. 5

Data are normalized to maximum tension achieved before caffeine treatment in the NTG and TG-ssTnI myofilaments. Caffeine did not affect maximum tension in either case. Ca-response is indicated by pCa50. Results demonstrate that the effect of caffeine to increase the response to Ca2+ (differences in pCa50) is the same in myofilaments from NTG controls and TG-ssTnI hearts. * indicates p<0.05 for pCa50 values in the presence of caffeine compared to controls.