Figure 1. Effect of a mephedrone exposure (4 doses of 50 mg/kg, s.c. at 2 h interval) on dopamine transporter density, measured as [³H]WIN35428 binding in mouse striatum (A), or frontal cortex (B) and 5-HT transporter density, measured as [³H]paroxetine binding, in hippocampus (C) and frontal cortex (D).

Results are expressed as mean±S.E.M. from 8–10 animals. *p<0.05; **p<0.01 and ***p<0.001 vs. saline.