Figure 4. Effect of a mephedrone exposure (3 doses of 25 mg/kg s.c. at 2 h interval for 2 days) on total tryptophan hydroxylase TPH2 expression (A) and its phosphorylated form (B) in hippocampus.

Panel C shows a representative Western blot. Results are expressed as mean±S.E.M. from 8–10 animals. *p<0.05 and **p<0.01 vs. saline.