Figure 7. Effect of mephedrone on immobility time in mouse forced swim test.

Animals were randomly divided into two groups (12–16 animals/group) and administered subcutaneously with saline (5 ml/kg) or mephedrone (3 doses of 25 mg/kg for 2 days) and tested 1, 3 or 7 days after exposure. Each animal was recorded for 6 min and the total period of immobility (in seconds) was registered. Each mouse was used only once for each experimental session. Each bar represents mean±S.E.M. immobility time. *p<0.05 and ***p<0.001 vs saline (one-way ANOVA and post hoc Tukey test).