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. 2014 Jun 3;9(6):e98809. doi: 10.1371/journal.pone.0098809

Figure 5. Drug induced tolerance of copper treated KO cells.

Figure 5

Cells were treated with Zn, DPA and Zn+DPA and viability was determined by MTT assay. Zn pretreatment was for 2 h. DPA and Cu exposure was for 48 h. The gain of viability following treatment (black) is given relative to the viability of untreated KO (open) and HepG2 cells (shadow). Significance (p<0.05) is indicated: *treated vs untreated; gain by treatment in KO vs. gain in HepG2 cells; aZn+DPA treatment vs. Zn; bZn+DPA treatment vs. DPA.