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Adenylate cyclase plays a role in ethanol mIPSC frequency increase. A: data show that Rp-cAMPS blocked the effects of ethanol on mIPSC frequency. B: % change of mIPSC frequency in the presence of 100 mM ethanol (control), forskolin (FSK, 10 μM), FSK + ethanol, Rp-cAMPS (Rp, 10 μM) + ethanol, and Rp (10 μM) + U73122 (U, 10 μM) + ethanol, (*P < 0.05, 1-way ANOVA, Dunnett's post hoc test).
