Fig. 5.

Intravenous preapplication of prazosin (150 μg/kg; n = 6) did not alter development of AIH-induced pLTF (black line), but did significantly inhibit development of hypoglossal (XII) LTF (gray line). Thus α₁ receptor activation was not necessary for AIH-induced pLTF, but it was for hypoglossal LTF (***P < 0.001, **P < 0.01 significantly different from baseline; ^##P < 0.01, ^#P < 0.05 significantly different from 30 min; ^@P < 0.05 significantly different from 15 min; one-way repeated measures ANOVA Fishers LSD post hoc test).