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. 2014 Apr 3;116(11):1353–1364. doi: 10.1152/japplphysiol.01093.2013

Table 3.

Phenylalanine concentrations, leg blood flow, and phenylalanine net balance

Time Postingestion
Rest 1–2.5 h (Early) 2.5–4 h (Late) 1–2 h 2–3 h 3–4 h 1–4 h (Entire)
Femoral arterial blood phenylalanine concentration, nmol/ml
    Blend 57.2 ± 1.3 70.8 ± 2.0a,c 60.0 ± 2.7 74.4 ± 2.4a,d,e 63.8 ± 2.6a,f 58.5 ± 3.0 65.6 ± 1.9a
    Whey 59.0 ± 2.6 64.0 ± 3.0a,c 56.6 ± 2.9 68.1 ± 3.0a,d,e 57.5 ± 2.8 56.0 ± 3.1 60.6 ± 2.9
Femoral venous blood phenylalanine concentration, nmol/ml
    Blend 62.6 ± 1.7 71.2 ± 1.8a,c 63.0 ± 2.0 72.7 ± 2.2a,d,e 67.2 ± 1.8a,f 61.3 ± 2.4 67.1 ± 1.3a
    Whey 63.0 ± 2.5 66.3 ± 3.1a,c 60.0 ± 2.7 70.0 ± 3.3a,d,e 60.8 ± 2.9 59.0 ± 2.7 63.6 ± 2.9
Leg blood flow, ml·min−1·100 g leg muscle−1
    Blend 2.41 ± 0.22 3.47 ± 0.98 3.23 ± 0.49 3.57 ± 1.23 3.26 ± 0.59 3.27 ± 0.46 3.37 ± 0.73
    Whey 2.66 ± 0.41 3.23 ± 0.52 3.79 ± 0.55 3.11 ± 0.45 3.65 ± 0.64 3.75 ± 0.57 3.50 ± 0.53
Phenylalanine net balance, nmol·min−1·100 g lean leg mass−1
    Blend −12.3 ± 1.5 2.3 ± 4.1a,c −8.0 ± 2.4 9.3 ± 5.7a,d,e −8.6 ± 3.7 −8.1 ± 2.4 −2.3 ± 2.7a
    Whey −10.5 ± 1.8 −6.5 ± 2.8 −12.0 ± 4.3 −3.5 ± 4.4 −12.7 ± 4.5 −11.7 ± 4.5 −9.1 ± 2.8

2 h

4 h
Intracellular muscle phenylalanine concentration, nmol/ml
    Blend 68.7 ± 2.8 77.0 ± 4.9 61.5 ± 3.0b 69.3 ± 3.2
    Whey 70.5 ± 5.7 74.6 ± 9.7 60.4 ± 4.7b 67.5 ± 6.3

Values are means ± SE. Femoral artery and vein blood and intracellular muscle phenylalanine concentration, leg blood flow, and phenylalanine net balance across the leg at rest and postingestion for subjects given Whey (n = 8) and a Blend (n = 8) at 1 h postexercise are shown. Comparisons are as follows: Rest vs. Early, Late, Entire, 2 h, 3 h, and 4 h; Early vs. Late; and 2 h vs. 3 h vs. 4 h.

a

P < 0.05 vs. Rest.

b

P < 0.05, main effect of time.

c

P < 0.05, Early vs. Late.

d

P < 0.05, 2 h vs. 3 h.

e

P < 0.05, 2 h vs. 4 h.

f

P < 0.05, 3 h vs. 4 h.