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. 2014 Mar 26;111(12):2493–2504. doi: 10.1152/jn.00764.2013

Fig. 4.

Fig. 4.

Block of 5-HT1AR increases excitatory nTS network activity. Individual responses to 5-HT1AR blockade with the specific antagonist WAY-100135 (10 μM) are displayed as raw values (left in each panel) and normalized to baseline (right, baseline defined as “1”) for TS-EPSC amplitude (A) and sEPSC event frequency (B). TS-EPSC amplitudes remain unaltered (n = 11; P = 0.97). Spontaneous event frequency, on the other hand, significantly increased, indicating a tonic role of 5-HT1AR. Bars show geometric mean with 95% CI; n = 9. **P < 0.01.