Table 1.
Demographic data
| Neurologically Intact Participants: Experiment I |
Participants with Stroke: Experiment II |
|||||
|---|---|---|---|---|---|---|
| Characteristics | DCS group (n = 19) | Placebo group (n = 22) | Group differences (P value) | DCS group (n = 10) | Placebo group (n = 10) | Group differences (P value) |
| Age (means ± SD) | 44.6 ± 13.7 | 43.7 ± 13.7 | P = 0.950 | 55.3 ± 9.6 | 51.4 ± 11.0 | P = 0.429 |
| Gender | ||||||
| Male | 10 | 15 | P = 0.116 | 7 | 4 | P = 0.398 |
| Female | 9 | 7 | 3 | 6 | ||
| Race | ||||||
| Caucasian | 4 | 4 | P = 0.655 | 7 | 4 | P = 0.398 |
| African American | 15 | 18 | 3 | 6 | ||
| Dominant side | ||||||
| Right | 15 | 20 | P = 0.033 | 6 | 9 | P = 0.003 |
| Left | 4 | 2 | 4 | 1 | ||
| Affected Side | ||||||
| Right | 9 | 3 | P = 0.028 | |||
| Left | 1 | 7 | ||||
| Months since stroke (means ± SD) | 25 ± 11 | 21 ± 13 | P = 0.727 | |||
| Stroke location | ||||||
| Cortical | 6 | 8 | P = 0.520 | |||
| Subcortical | 1 | 1 | ||||
| Posterior circulation | 1 | 0 | ||||
| Unknown | 2 | 1 | ||||
| NIHSS score (median, IQR) | 1,2 | 1,2 | P = 0.582 | |||
| ARAT score (means ± SD) | 34 ± 14 | 41 ± 8 | P = 0.148 | |||
| BBS score (means ± SD) | 46 ± 7 | 47 ± 8 | P = 0.561 | |||
| SB test score (means ± SD) | 2.6 ± 2.6 | 2.8 ± 3.4 | P = 0.228 | |||
Values are counts except where indicated. DCS, d-cycloserine; IQR, interquartile range; NIHSS, National Institutes of Health Stroke Scale: scores for the motor subset range from 0 to 18, with lower scores indicating less impairment; ARAT, Action Research Arm Test: scores range from 0 to 57, with lower scores indicating more impairment; BBS, Berg Balance Scale: scores range from 0 to 56, with lower scores indicating more impairment; SB, Short Blessed Test: scores range from 0 to 28, with lower scores indicating less impairment.